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Bernardi, R. et al. PML inhibits HIF-1alpha trandlationeoangiogenesisenesis through repression of mTOR.
Wang, B. et al. miR-200a Prevents renal fibrogenesis through repression of TGF-beta2 expression.
Gonzalez, S. et al. Oncogenic activity of Cdc6 through repression of the INK4/ARF locus.
We find that miR-145 functions through repression of Fli-1, a megakaryocyte and erythroid regulatory transcription factor.
Lu, Y. et al. Yin Yang 1 promotes hepatic steatosis through repression of farnesoid X receptor in obese mice.
Collectively, the above results confirmed our hypothesis that BMP-6 inhibited miR-21 expression, an effect that could be mediated through repression of δEF1.
Additional studies showed that BOL effectively sensitized MEK inhibitors through repression of p-STAT3 and MCL-1 induction, known resistance mechanisms of MEK inhibition.
Yan, Y. et al. Transcription factor C/EBP-beta induces tumor-suppressor phosphatase PHLPP2 through repression of the miR-17-92 miR-17-92 miR-17-92tiating AML cluster
Based on these findings, we propose that CBX6 potentially plays a tumor suppressor role through repression of BST2 in breast cancer.
Mechanistically, EGF reduced radiation-induced apoptosis of HSCs and mediated this effect through repression of the proapoptotic protein PUMA.
Suicide is encouraged, and ultimately the species survives through repression of the have-nots, and cannibalism disguised through clever packaging.
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