Sentence examples for through reconstitution from inspiring English sources

Metabolic engineering is the term giving a concept of alteration in metabolomics of any organism by regulating biosynthetic mechanism through reconstitution of changes at genetic level.

While the current state and trends of high throughput metabolomics profiling focus on the purpose of discovering biomarkers and hunting for metabolic mechanism, a prospective direction, namely reprogramming metabolomics, highlights the way to use metabolomics approach for the purpose of prevention and treatment of disease through reconstitution of perturbed metabolic pathways (Peng et al., 2015a).

The biological importance of this FAK-signaling pathway was confirmed through reconstitution experiments using FL-uPAR/cathepsin FL-uPAR/cathepsin B-transformed B-transformedession of uPAR and cathepsin B rescued Y925 phosphorylation, meningioma, Ang-1, Ang-2 and VEGF expression.

The biological importance of this FAK-signaling pathway was confirmed through reconstitution experiments using Src-transformed FAK-null fibroblasts where point-mutations affecting FAK catalytic activity or Y925 phosphorylation disrupted the ability of FAK to promote MAPK- and VEGF-associated tumor growth [33].

In the future, such questions may best be addressed through reconstitution of complete MT-nucleating complexes from purified components.

Nonetheless, depletion of VAV3 reduced RAC1 activity in both MCF7 and MCF7-LTED cells, and this alteration was recovered through reconstitution using a shRNA-resistant MYC-Vav3 expression construct (Additional file 11: Figure S6).

GRO and Il-6 act together following infarction to improve cardiac function through the reconstitution of tissue mass.

In addition, HvPORA plays a photo-protective role during greening through the reconstitution of the light-harvesting POR: Pchlide complex (Buhr et al. 2008).

The recovery and viability of human MNC, CFU-GM recovery, as well as the engraftment potential of thawed MNC evaluated through the reconstitution of hematopoiesis in patients treated with autologous HSPC transplantation were assessed.

Doctors already treat serious illnesses with cord blood and placenta blood stem cells through hematopoietic reconstitution -- the process of replacing diseased blood cells with healthy stem cells.

For the first time, however, our ability to dissect NB through the reconstitution experiments described here provides a conceptual framework that explains the origin and nature of the protein repertoire found associated with NB.