Sentence examples for through prolongation from inspiring English sources

In addition, β-blockers increase coronary blood flow through prolongation of the diastole.

The effect on risk is through prolongation of the period with relatively high exposure to endogenous oestrogen.

Protein kinase C activation by phorbol 12-myristate 13-acetate up-regulated Wnt5a partly through prolongation of Wnt5a mRNA half-life.

mtr1-deletion leads to subtle but significant stabilization of interphase microtubules, particularly through prolongation of dwell-time of microtubule plus ends at the cell tip cortex, and the decrease in the frequency of catastrophe (Fig. 1).

The inhibitor enhances the response of tumor cells to radiation through the prolongation of γ-H2AX foci.

This indicates that a delayed intervention in a clinical situation leading to a secondary haematoma in the fractured region may delay the healing process through the prolongation of the pro-inflammatory phase.

These results indicate that MDA attenuates the capacity of encoding sequential spikes through the prolongation of absolute refractory periods (Fig. 4).

Hypokalaemia is known to predispose to cardiac arrhythmias at the clinical (Berthet et al. 1999) and experimental (Killeen et al. 2007a) levels through the prolongation of APD and the subsequent development of EADs, which superimpose upon an arrhythmogenic substrate of altered transmural gradients of repolarization (Killeen et al. 2007b).

Increases in the time spent in the voltage window range for L-type Ca2+ channel reactivation through AP prolongation are likely to generate EADs, which may in turn give rise to salvos of premature potentials termed triggered beats (January et al. 2000, Fabritz et al. 2003).

Thus, chronic lead exposure may give rise to disturbances in ventricular conduction and result in QT prolongation, through cardiac afterload, via lead-induced elevation in vascular resistance.

AP prolongation through IKss inhibition is likely to affect sarcolemmal Ca2+ fluxes via L-type Ca2+ channels and the Na+/Ca2+ exchanger and thereby to contribute to the effects of noradrenaline on atrial contractility and arrhythmogenesis.