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Experimental evidence suggests that the maintenance of an item in working memory is achieved through persistent activity in selective neural assemblies of the cortex.
Furthermore, mutant SOD1 in microglia disrupts regulation of NADPH oxidase activity through persistent activation of RAC1, resulting in prolonged production of reactive oxygen species, which promote motor neuron apoptosis (Harraz et al., 2008; Marchetto et al., 2008).
The paper demonstrate a form of graded persistent activity activated by hyperpolarization.
Recurrence is dominated by inhibition, although persistent activity is generated through recurrent excitation in small subsets of excitatory neurons.
We conclude that dopamine-induced suppression of persistent activity is mediated through D1-like receptors.
During persistent activity, spiking of many neurons is highly irregular.
Population analyses revealed that FEF neurons with persistent activity were more effective at selecting the target from among distracters than neurons lacking persistent activity.
Guo, Z. V. et al. Maintenance of persistent activity in a frontal thalamocortical loop.
Beyond working memory: the role of persistent activity in decision making.
Compte, A. Computational and in vitro studies of persistent activity: edging towards cellular and synaptic mechanisms of working memory.
Despite the 18 million Euros spent since 1999 on geotechnical investigations and stabilization solutions, the numerous reactivations that occurred through 2010 and 2013 demonstrate the persistent activity of the landslide.
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CEO of Professional Science Editing for Scientists @ prosciediting.com