At such sites a large part of the gas will often emit through other pathways such as the leachate collection system.
"We think the beneficial effects act through other pathways, beyond the effects on blood pressure," says study author Sylvia Wassertheil-Smoller, Ph.D., an epidemiologist at Albert Einstein and a principal investigator with the Women's Health Initiative.
Lastly, chemicals in I-F and I-G had negligible NR activity, which could suggest that they act through other pathways.
Combined with the results above, this suggested that resistance to CTL cytotoxicity is mediated through other pathways, such as the perforin/granzyme pathway.
This indicated that CD4/10.4 T cells may exert their cytotoxic capabilities through other pathways besides degranulation, such as the Fas/FasL pathway [31].
The authors concluded that LAP inhibits the portion of known TGF-β1 signals that result in fibrosis, but that TGF-β1 likely signaled through other pathways to mediate inflammation.
This would mean that IAP binding is a secondary function of these proteins and they may route through other pathways of apoptosis induction where caspase activity is only auxiliary to their apoptogenic potential.
Moreover, it may undergo secretion through other pathways, such as intracellular vesicular routes (exosomes formation, secretory lysosomes) or other where intermediate intracellular vesicles are not involved (membrane blebbing/shedding, translocation mediated by plasma membrane-resident transporters) [30].
However, the pathway taken may also be influenced by the presence of vaccine adjuvants, which trigger TLRs of the immune cells or act through other pathways such as antigen processing and presentation [9], [15].
Lastly, it is possible that the observed inverse association of plasma 25-[OH] D with GDM risk reflects the impact of other components of major endogenous and exogenous sources of vitamin D on glucose homeostasis through other pathways.
Firstly, the opposing promoter arrangement leads to the production of two complementary RNAs that have the potential to form not only dsRNA and mediate RNAi-directed gene silencing, but also small RNA effectors that can operate through other pathways.
