Sentence examples for through its affinity from inspiring English sources

Rap80 joins the damage site through its affinity for K63-linked chains and brings with it a breast cancer suppressor protein (BRCA1) complex (Sobhian et al, 2007).

Its high cation exchange capacity value of 4.8 meq/g was confirmed through its affinity for cadmium and strontium cations.

Our results show that ligands αvβ3 are not only necessary but sufficient for the induction of resorptive behavior in osteoclasts; and suggest that bone is recognized through its affinity for these ligands, rather than by its mechanical or topographical attributes, or through a putative 'mineral receptor'.

Brd4 functions to recruit P-TEFb to active promoter through its affinity to acetylated histones [ 35, 36].

CD44 mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA), and also other ligands such as collagens and MMPs.

As a contrast to the covalent immobilization on Sepabeads, which is random in orientation, we have used non-covalent oriented attachment of TvDAO through its affinity tag (Strep-Tag II) to Strep-Tactin coated on porous MacroPrep particles [ 23].

Classical transcriptional actions of 1,25D3 are mediated through its high affinity interactions with the vitamin D receptor (VDR).

At nanomolar concentrations CVN binds these oligosaccharides only through its high affinity site, while at micromolar to millimolar concentrations the oligosaccharides are bound through both sites leading to divalent protein carbohydrate interactions.

The adjuvant function of C3d is primarily mediated through its high affinity interaction with complement receptor CR2 (CD21/35) expressed on B cells and FDCs [34], [35].

In that study the authors applied competition phage-binding assays and demonstrated the bivalent display through its apparent affinity boosting avidity effect that, as expected, occurred only on surface immobilized targets as opposed to solvent-phase targets.

The modified peptides were then captured by avidine through its strong affinity to biotin.