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Here, the authors identify and characterize a primate-specific long noncoding RNA, called CHROME, that controls cholesterol homeostasis through fine-tuning of miRNAs and whose levels are elevated in human atherosclerosis.
Unlike traditional Publish-Subscribe middleware, DDS can explicitly control the latency and efficient use of network resources through fine-tuning of its network services, which are critical for soft real-time applications (e.g., its QoS policies deadline, latency budget or transport priority) [16].
Whether merlin modifies NRG1 type III levels through fine-tuning the activity of proteases remains to be established.
For example, Arabidopsis IPS1 and M. truncatula Mt4 mlncRNAs are involved in phosphate starvation through fine-tuning the expression of miR399/PHO2 gene [ 54, 56, 113].
The possible explanation is that the amino acid residue at position 285 does not directly interact with the nucleotide but rather affect anticodon recognition through fine-tuning the local conformation of the anticodon recognition region of AcPheRS.
They find that microRNAs can repress gene expression either as a switch or through fine-tuning and that the strength of repression can vary widely between cells.
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The results are obtained through fine tuning of threshold and width of the Gaussian kernel and embedding using LSBMR.
We conclude that cholesterol can either inhibit or facilitate membrane-Aβ interactions through fine tuning of glycosphingolipid conformation.
Gene regulation in eukaryotes is achieved through fine tuning of activator and repressor complexes that mediate relaxed and condensed chromatin state respectively.
Lastly, suggestions for optimization of the existing system through the fine-tuning of the control strategy of its main components are presented.
Terminal users demonstrated high levels of thermal tolerance and wide acceptability temperature ranges, averaging 6.1 °C in summer and 6.7 °C in winter, which allow for heating energy savings through the fine-tuning of indoor temperature set-points.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com