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Instead of relying on how X-rays are absorbed by different materials, they have instead focused on how they are diverted or refracted as they pass through different substances.
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In their travel through the column, the different substances distribute themselves according to their relative affinity for the two phases.
In fact, almost the only methods of classification available to historical chemists, before compound structures were well understood, were (i) based on the observation of reactivity through means of performing controlled reactions between different substances; or (ii) based on the origin of the molecule, when the molecule was isolated from a natural product substance.
The Scottish scientist Joseph Black, in the 18th century, noticed that equal masses of different substances needed different amounts of heat to raise them through the same temperature interval, and, from this observation, he founded the concept of specific heat.
Such forces vary widely for different substances.
Different fly species land on and taste different substances.
So Mr. Sutherland tried adding different substances to the foam.
Creating the heterojunction between different substances is an effective method.
The mathematician, moonlighting as an alchemist, turned things both animate and inanimate into different substances.
It's the same concept -- you just program it to alert you on different substances".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com