Sentence examples for through counteracting from inspiring English sources

Restoration of p53 activity by small molecules through counteracting p53 repressors can lead to in vivo tumor regression and is therefore considered a promising strategy for treatments of cancer.

Synthetic and medicinal chemistry studies led to the identification of four potent antagonists, compounds 7d, 10, 12 and 13, which were able to significantly inhibit the stimulatory effect of NPS through counteracting the increased intracellular Ca2+ accumulation.

Therefore, the mechanisms of transportation of its seeds may result in topography-dependent genetic structures, whereas wind-mediated pollen flow of C. chinensis may reduce such structures through counteracting the influence of topography.

It protects against renal fibrosis through counteracting the profibrotic effects of TGF-β1 in glomerular mesangial cells and renal epithelial cells.

HRH4 has been reported to influence apoptosis in animal models of sepsis through counteracting the anti-apoptotic action of NF-kappaB [ 30], while the cAMP-PKA pathway is involved in HRH4 activation-mediated cell death in peripheral blood mononuclear cells (PBMCs) [ 29].

SUMO conjugation controls diverse cellular functions, sometimes through counteracting or contributing to ubiquitin conjugation.

Overall, these results suggest that the effect of conditioning temperatures on broiler performance is determined through their counteracting influence on nutrient availability and pellet quality.

In summary, we demonstrate for the first time that read-throughs act as regulators by counteracting their parent genes in suppressing or activating genes or mechanisms in renal cancer.

Although a role for GPC1 in the regulation of wnt signalling has not been reported so far, it is possible that PRDM5 may down modulate non-canonical wnt/PCP signalling through downregulation of glypicans, counteracting the positive effect of Dkk1 on this pathway.

Iron fertilization is contentious because it is associated with geoengineering, a set of proposed strategies for counteracting global warming through the deliberate manipulation of the environment.

While this cellular alteration has fitness costs in the absence of stress (stable cell lines could not be isolated under basal conditions), this means of counteracting reduced flux through the proteasome under stressful conditions is conserved from yeast to humans.