Sentence examples for through attenuation of from inspiring English sources

Thus, lercanidipine revealed significant neuroprotective effect mediated through attenuation of oxidative stress, inflammation and apoptosis.

In summary, our data suggest that metallothionein protects against cold exposure-induced cardiac anomalies possibly through attenuation of myocardial fibrosis.

Collectively, these findings suggested that metallothionein protects against ER stress-induced cardiac anomalies possibly through attenuation of cardiac autophagy.

We hypothesized that the effects of clinically applicable thermal preconditioning are mediated through attenuation of this leukocyte-endothelial (L-E) interaction.

We hypothesized, based on previous experimental [9 11] and clinical data [12], that the anti-inflammatory activity of steroids is mediated through attenuation of innate immune system activity, specifically the attenuation of neutrophil activation.

Recently it has been reported that autophagy induction by SIRT6 through attenuation of insulin-like growth factor signaling is involved in human bronchial epithelial cell senescence (Takasaka et al., 2014).

Conclusions Carvedilol improved sepsis-induced cardiomyopathy through the attenuation of telomere shortening by regulating gene expression of energy metabolism and reducing mortality resulting from sepsis.

In conclusion, these findings clearly confirm that DSePA exhibits protective effects against whole-body γ-radiation and the probable mechanisms of action involve the maintenance of antioxidant enzymes, prophylactic action through the attenuation of the DNA damage, and inhibition of apoptosis.

This case better mimics the upper and lower shear layers that might be seen behind a heavy vehicle than previous away-from-ground tests, which have shown significant drag reduction is achievable through the attenuation of von Kármán shedding in the near wake.

Since demyelination and acute axonal injury in MS are considered to result mainly from the acute inflammatory process, it raises the notion that the neuroprotective effect of transplanted NPs in EAE is mediated, at least in part, through the attenuation of the inflammatory process and prevention of its secondary neurodegenerative effects.

Our functional analysis of a human disease-associated gene variant demonstrates that IL23R R381Q exerts its protective effects through selective attenuation of IL-23-induced Th17 cell effector function without interfering with Th17 differentiation, and highlights its importance in the protection against IL-23-induced tissue pathologies.