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Recent findings indicate that most anticancer agents induce apoptosis, directly or indirectly, through alterations of tumor cell membrane fluidity.
A previous in vitro study revealed that Arg elicits positive effects on casein synthesis through alterations of the Arg-ornithine pathway in bovine mammary epithelial cells.
We focused on these two factors because adenosine signaling can regulate production of KGF (29), and adenosine primarily signals through alterations of intracellular cAMP, which can regulate expression of IGF-1 (refs 30, 31).
Together, our findings support that syndecan-1 knockout leads to alterations in mechanosensing of nanotopographical cues through alterations of in rho-associated signaling pathways, cell mechanics and mediators of the Hippo and TGF-β signaling pathways.
To overcome these limitations, we fine-tuned biosensor performance through alterations of the promoter and operator of output module and the ligand affinity of transcription factor module, which enabled us to deduce recommendations for building and application of actinobacterial biosensors.
The amplified responses of polar ecosystems, and the potential feedbacks presented through alterations of soil processes, make it important to understand the consequences of climate change in polar soil systems.
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In sepsis research, the focus is on the elements that cause disease and alter phenotypes through alteration of molecular function.
It has long been thought that disease causing variants act through alteration of exon sequence resulting in altered protein function.
Varying hydrogel rigidities were produced through alteration of acrylamide/bisacrylamide amounts (Supplementary Table S1) based on Engler's protocol35.
Epigenetic dysregulation is a common feature of most cancers, often occurring directly through alteration of epigenetic machinery.
Our results suggest that atrazine reduces egg production through alteration of final maturation of oocytes.
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