To investigate whether age and gender of participants, positivity thresholds, prevalence of infection, intensity of infection, quality of the reference standard, effects of praziquantel treatment, infection stage, mixed infections, and the methodological quality of included studies can explain observed heterogeneity in estimates of test accuracy.
SCI takes the latter approach, delineating areas according to the World Health Organization (WHO)–recommended threshold prevalence of 50% for annual mass treatment.
The overall prevalence of active trachoma in Dera woreda was lower than WHO threshold prevalence of 20% which is used to determine trachoma as a severe public health problem [ 26].
Thus the threshold prevalence of ≥ 20%, recommended by WHO for annual STHs de-worming could be none cost effective if Hall and Horton's economic calculations on treatment rounds based on prevalence are to be considered [ 38].
As shown by Graat et al. [ 13], for infectious bovine rhinotracheitis (IBR), the threshold prevalence of antibody positive cows at which the ELISA used can classify the bulk milk as positive, is a parameter that needs severe consideration, since it affects the detection time and the performance of the surveillance system.
Depending on the stringency of threshold, prevalence rates of irritability range from 3%% for severe, chronic irritability strictly defined in the Great Smoky Mountain study [ 7] to 20 % in the Isle of Wight study [ 8].
Our findings support viral testing only in the former group, consistent with the threshold prevalence for both HBV and HCV, of approximately 3% at which population screening becomes cost-effective [ 21, 43, 44].
At the strata age of 40 49 years threshold, the prevalence of ST and MT swaps in favour of ST infections.
The threshold population prevalence of C. trachomatis infection over which the evaluations were cost-effective varied from 3.1 to 10%.
We used the Pearson chi-square test to detect whether there was a significant association between patients above/below the VO2peak threshold and prevalence of risk factors.
The combinatorial STD crosses this threshold for prevalence of 1.5%, while for the hybrid designs with weight ratios 0.2, 0.3 and 0.5, this happens for prevalence of 1.9, 2.3 and 1.5%, respectively.
