We measured symmetry detection thresholds for target dot patterns with one of four possible symmetry axis orientations.
35, 36 Therefore, PhIN introduces molecule –molecule functional similarity by defining that functional similarity of two molecules is determined by their interactive targets in common (the default thresholds for target numbers and pChEMBL values are 3 and 6, respectively).
Thresholds for target patterns that were in phase with the inducer matched baseline performance (mean suppression = 0.01 log units or 2%), whereas thresholds for antiphase test patterns were highly elevated (mean suppression = 0.31 log units or 106%).
In Experiment 1, we measured contrast thresholds for targets of varying size.
Rather, the two purposes of this experiment are 1) to provide a small set of empirical thresholds for targets whose images are likely to span the dimensions of interest (size, brightness, shape, orientation), and 2) to test whether the SSO is able to make accurate predictions of those thresholds.
Differential thresholds for targets allowed for the fact that some indicators (e.g. ANC) started at much higher levels than others (e.g. facility deliveries).
For the second benchmark, a ROC curve for CAD was created by considering four thresholds for targets with at least one, five, ten and fifteen Pubmed citations as CAD true positives and targets with less than five, ten and fifteen citations or without any citations as CAD false positives (Additional file 1 - Figure S1(B)).
For the second benchmark, ROC curves for the seven complex diseases were created by considering four thresholds for targets cited by at least one, five, ten and fifteen article citations as true positives and targets without any citations or less than five, ten and fifteen citations as false positives.
Another series has suggested that the SUV threshold for target volume definition to define tumour length needs to be decided on an individual patient basis [61].
To reduce false positive targets, we set the threshold for target alignment score to 4 so that only target genes that have alignment score no greater than 4 were retained as putative targets.
Using Canada's southern provinces as an application case, the study explored several factors important for the design of environmental monitoring system using optical sensors of earth observation, in particular, cloud dynamics and its inter-annual variability, sensors' revisiting intervals, and cloud-free threshold for targeting composites.
