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There is no universally accepted threshold for defining consensus as part of the Delphi process, with thresholds for consensus ranging from 55%-100% in the published literature [ 7].
We attempted a variety of filtering schemes for SNP-calling, incorporating thresholds for consensus base quality, mapping quality of supporting reads, and consensus quality of adjacent bases.
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Secondly, there are no current recommendations for determining the threshold for consensus agreement.
Statements were considered to be "principles governing CBE" once the 70% threshold for consensus was reached.
All statements that reached consensus are presented in Table 2 within the seven domains. 5 statements were removed throughout the process due to not reaching the threshold for consensus and the thematic analysis of the free text responses.
The lines indicate how to evaluate these items (>80% agreement) * Only a 79% agreement was reached to perform a mortise-view, which did not reach the 90% threshold for consensus.
A second post hoc definition of indicator acceptance and agreement, using the same thresholds as above (for consensus criterion 1), but with the further requirement of 'good' agreement about the link to outcomes, defined as an inter-quartile range on the link to outcomes attribute not exceeding two (consensus criterion 2).
The following hyperparameters were used: and a threshold for the consensus network of 0.01.
The fact that the threshold of 90% agreement for consensus could not be reached for either an AP- or a mortise projection is remarkable.
We used established consensus thresholds for improvement in Roland-Morris disability questionnaire scores at three and twelve months to derive NNTs for improvements and for benefits (improvements gained+deteriorations prevented).
The consensus thresholds for multiple-run and bootstrap experiments were chosen taking into account network properties such as size, density, modularity, average-degree and topology.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com