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A sensitivity analysis in the present study using a variety of p value thresholds for calculating polygenic scores demonstrated that observed effects are consistent across various thresholds.
Statistical indicators included C-statistics, sensitivity, and predictive positive value[ 1], and the thresholds for calculating statistical indicators were set as the corresponding levels of outcomes.
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The threshold for calculating cycle threshold (Ct) values was calculated automatically using MyiQ software (version: 1.0.410).
Each value is taken as a threshold for calculating true positive fraction (TPF) and false positive fraction (FPF .Then ROC curve is plotted and AUC value is calculated according to these TPFs and FPFs.
The threshold for calculating the percentage positive cells was based on the maximum staining obtained with irrelevant isotype-matched mAb, used at the same concentration as the test mAb.
Although p <.5 is frequently used as a threshold for calculating polygenic scores (29,43 45), this is largely a convention established on the basis of the optimal threshold in the study of schizophrenia that inspired the wider application of polygenic score analysis (29).
For SNNC, there are three parameters: the size of the nearest neighbors κ, the similarity threshold Eps for calculating the SNN density, and the density threshold MinPts for finding the core points.
The histograms of gray values from the CT scanning images showed distinct peaks of air voids and asphalt materials, based on which the threshold value for calculating the voxels of air voids was determined by the ISO50 threshold method.
Figure 4 Threshold curve for calculating an erroneous disparity (Equation 7).
27 Therefore, LSAS-SR ≤30 was used as a threshold value for calculating the remission rate throughout the study.
Results from this pilot study will lead to a better-designed main study and serve as a discussion point about setting a threshold value for calculating the sample size.
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