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The thresholds at this stage are shown as vertical and horizontal lines in Fig. 10-bottom part.
Further research is warranted to identify possible subgroups of patients at risk of being above recommended BRT thresholds at this time.
However at age 7 and 9 years a measure of extra-high-frequency hearing at 16 kHz was available and comparison of the hearing thresholds at this frequency showed c.35delG carriers had hearing thresholds approximately 5 10 dB worse than non-carriers.
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Wiki-PR is over that threshold at this point".
Data was transformed to logarithmic values for cough threshold at this test.
What evidence would be needed to support or refute the existence of a biological threshold at this event?
The 5% quantile point of the minimum P value represents the genomewide significance threshold at this marker density.
We decided to set the threshold at this value to include all information considered relevant from our approach.
The largest mean difference between placebo/moxifloxacin and placebo alone (13.90 ms) was observed at 2 h post-dose; the corresponding upper bound of the two-sided 90% CI (17.22 ms) exceeded the regulatory threshold at this timepoint and at several other timepoints (Table 2, Figure 1) [ 9].
A genome-wide critical F ratio threshold was calculated by first obtaining a Bonferroni corrected P-value at the 5% significance level (given the 29 pairs of chromosomes of Atlantic salmon, adjusted P-value=0.05/29) and then obtaining the genome-wide F ratio threshold at this adjusted P-value, using 10 000 permutations (Churchill and Doerge, 1994).
Any neurons exceeding these thresholds at any point during this time window are reported as significant.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com