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The statistical threshold was corrected for multiple comparisons using the Bonferroni correction based on 2 × 9 = 18 comparisons (two-tailed, nine networks) yielding a corrected P value threshold of 0.05/18 = 0.003. A. Hafkemeijer, J. van der Grond, and S. Rombouts made substantial contributions to conception and design, analysis, and interpretation of the data.
The significance threshold was corrected for multiple comparisons using the false discovery rate approach (Benjamini et al. 2001).
The significance threshold was corrected for multiple testing by dividing the 5% significance-level threshold by the number of principal components, which explained 95% of the variance in metabolite data.
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Compositional effects on the breakdown threshold are corrected employing a straightforward procedure.
The significance threshold is corrected by FDR with α = 0.05.
Resultant z-score P values (0.05 threshold) were corrected using the False Discovery Rate.
The significance threshold is corrected to 1/(number of genes) to make it improbable that false positives arise.
The hearing thresholds were corrected for age-related deterioration and compared to the results without adjusting for age.
For the LH we also investigated the spatial location of volume changes using voxel-wise t tests between a group of 50 male and 50 females; t thresholds were corrected for multiple comparison.
The naïve calculated uncertainty profile (the red dashed line in Figure 6B) is in good agreement with the probability that a given positive prediction (one to the right of the threshold) will be correct, but underestimates the confidence one can have that a negative prediction (one to the left of the threshold) is correct.
In some cases where there was artificial reduction in signal intensity due to artefacts in the MRI image, the threshold map was corrected by using the autotrace facility within the Analyze software.
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