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A Thompson score ≥ 5 at 1 or 3 hours identified all infants with an abnormal aEEG at 3 and/or 6 hours – this may be an appropriate threshold to guide early referral to cooling centers for further assessment.
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* U.S. central bank adopting series of policy guidelines * Next on agenda: economic thresholds to guide rate hikes * Bernanke expected to step down in January 2014.
Finally, we propose a third strategy that uses patterns discovered under more relaxed criteria (such as lower support-confidence thresholds) to guide the extension step.
In addition, to avoid interference with our aim to externally validate the Wells rule combined with D-dimer testing, we explicitly provided no guidance on how to use the score (which score thresholds) to guide subsequent management.
A number of studies have addressed empiric and quantitative approaches for using surveillance data in treatment guidelines for urinary tract infections and pyelonephritis, including cost-effectiveness studies and establishing resistance thresholds to guide therapy decisions (23– 23).
Large well-controlled observational studies that are powered to examine important subgroup effects (for example, RBC transfusion by hemoglobin concentration) and time-varying covariates (for example, ICP) are warranted to characterize both hemoglobin concentrations and transfusion thresholds to guide clinicians managing patients with a TBI.
Furthermore, GRGs independently predicted the time interval from seroconversion to CD4+ cell count thresholds used to guide HAART initiation.
The outcomes analyzed were risk of development of AIDS, and rate of progression to AIDS as well as to CD4 cell count thresholds used to guide initiation of HAART [6], [7], [8], [9].
In addition, current thresholds used to guide chelation therapy in transfusion-dependent patients are based on the association between serum ferritin/liver iron concentration (LIC) and cardiac complications or death 25.
Two cardiologists independently adjudicated the diagnosis of myocardial infarction by using a high sensitivity troponin I assay with sex specific diagnostic thresholds (men 34 ng/L, women 16 ng/L) and compared with current practice where a contemporary assay (50 ng/L, single threshold) was used to guide care.
A recent systematic review identified six RCTs and six prospective observational studies analyzing different thresholds of GRV to guide enteral nutrition and to prevent complications (for example, vomiting, aspiration, and nosocomial pneumonia) in mechanically ventilated patients [ 127].
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