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Dashed line depicts usual threshold to define normal values in adults.
There was wide interindividual variation in platelet aggregation in response to aspirin, with no clear biological threshold to define aspirin resistance.
When one uses a threshold to define a disease, one does not clearly demarcate disease from normality because the threshold includes overlapping spectra of mild disease and normality.
The range of normality is 55 85 cm/sec, whereas mFV >120 cm/s is currently used as a threshold to define TCCS vasospasm (1).
A fluid deficit of more than 1000 ml should be used as threshold to define fluid overload when using hypotonic solutions in healthy women of reproductive age.
Alternatively, the threshold to define the fault area is inadequate for the southern area; that is, the fault area may be a half of that estimated.
[C] A fluid deficit of 2500 ml should be used as threshold to define fluid overload when using isotonic solutions in healthy women of reproductive age.
In general, the threshold to define fluid responsiveness with the passive leg raising test is a 10% increase in stroke volume and/or cardiac output.
A fluid deficit of more than 1000 ml should be used threshold to define fluid overload when using hypotonic solutions in healthy women of reproductive age.
In this approach NNT is dependent on the threshold to define response on the continuous scale.
Lowering the threshold to define hypertension multiplied by 2.5 the number of eligible individuals.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com