Both the alignment and fiber density (expressed as fraction of pixels above a given threshold) decrease (figure 5).
The extreme aggregation of vectors on hosts, described by the power-law decay of the degree distribution, makes the epidemic threshold decrease with the size of the network and vanish asymptotically.
At 6 mg/kg (therapeutic dose), the cold hypersensitivity was manifested by a 50% threshold decrease.
Every 1 kOhm elevation of electrode impedance resulted in a mean NRT threshold decrease of 0.11 ± 0.02 C.L. (Table 1).
Mechanical hyperalgesia (nociceptive threshold decrease) in non-pretreated arthritic mice reached an approximately 25 30% after 5 days, which further increased to 45% by days 10 in both male and female mice (Fig. 2A and B).
Lower doses, in particular 1 mg kg-1, was able to strongly prevent pain behavior when evaluated both as an increase on suprathreshold stimulation (hyperalgesia-related measure) or as pain threshold decrease (allodynia-related measure).
