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The Dutch team artificially introduced three mutations.
Thus, these three mutations coordinately enhanced the lysine yield.
We generated three mutations: Asn182Asp, Asp183Lys, and Ala36Glu.
Similarly, important thermal stability decreases were observed for three mutations.
Immunogene panel sequencing identified three mutations (IRF1, SLAMF6, SEC14L3) in the patient's CD8+ cells (Fig. 2a).
Whole exome sequencing showed three mutations in genes potentially involved in his clinical phenotype.
Different combinations of the three mutations correlate with different degrees of susceptibility to diabetes, the researchers found.
The introduction of three mutations (T247A, A243S, F173A) led to seven new mutant proteins.
Three mutations are novel, including SOD1 p.G10A, SOD1 p.D83N, and OPTN p.L494W.
All three mutations in the HPV-positive cases were associated with intermediate-risk viruses.
In the other lineages, we find that only three mutations cause the improved phenotype.
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