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It is just one example of the life threatening results of pregnancy, delivery, and the first 1000 days of life without the benefit of the basic services that we too often take for granted.
SAEs include any untoward medical occurrence that results in death or is life threatening, results in significant disability/incapacity, requires inpatient hospitalisation or prolongation of existing hospitalisation.
Serious adverse events are defined as any medical occurrence that is life threatening, results in death, or persistent or significant disability, or any medical event, which might jeopardise the patient, or require intervention to prevent it [ 43].
A cerebral concussion almost certainly impacts on astrocyte structure and function, but such injury is not life threatening, results in minimal if any abnormalities on neuroimaging, and is thus (by definition) not usually the subject of neuropathological review or investigation.
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Serious adverse events were defined as medical events that are life threatening; result in death; disability or significant loss of function; that cause hospital admission or prolonged hospitalization; a hereditary anomaly; or fetal injury [40].
Serious AEs were defined as any that resulted in death; were life threatening; resulted in hospitalization; resulted in persistent or significant disability or incapacity; or were judged to be medically significant.
Serious adverse events (SAE's) are those events that result in death or are life threatening, result in hospitalization or prolongation of hospitalization, result in persistent or significant disability, or result in a congenital birth defect.
A serious adverse event was one which resulted in death, was life threatening, resulted in persistent or significant disability/incapacity, inpatient hospitalisation or prolongation of existing hospitalisation, congenital anomaly or birth defect, or an important medical event.
24 Adverse events were graded as serious if they were fatal or life threatening, resulted in prolonged hospital stay, caused persistent disability or incapacity, or required medical or surgical interventions to prevent serious outcomes.
Investigators rated the intensity, relation to study drug (possibly, probably, or definitely drug-related; probably not or definitely not drug-related), and seriousness (includes events which are life threatening, result in hospitalization, or cause permanent incapacity, or other significant event) of adverse events.
He says having a high-profile politician invading the psychological territory of civil servants will make them feel threatened, resulting in defensive, hostile behaviour.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com