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When faced with a decision about the use of morphine in a potentially life threatening exacerbation, his wife referred to their plans for future care.
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Indeed, outcomes that were positively impacted by corticosteroid treatment (lung function, hypoxemia, relapse rate) are not those that one expects to alter in life-threatening exacerbations.
COPD patients may be confronted with acute life-threatening exacerbations.
Airway secretions also contribute to the pathology of asthma, and especially to the consequences of acute, severe, life-threatening exacerbations.
Uncontrolled asthma leads to a lower quality of life, may induce lung damage, can cause life-threatening exacerbations and results in increased healthcare resources utilization and expenditures [ 4].
Wilson et al. developed a DA to assist patients with COPD in advance planning for life-threatening exacerbations of their disease [ 29].
Each case was matched by sex, age, and ethnicity, with 2 controls who had attended with a non life-threatening exacerbationon life-threatening
Serious asthma exacerbations (life threatening or requiring hospitalization) were the primary end point.
We previously reported the efficacy of NIV for life-threatening acute exacerbation of interstitial pneumonia or asthma attack [ 11, 12], for which the evidence level for its usefulness was not high [ 3].
Children were excluded if they had a hypoxic seizure or a life-threatening asthma exacerbation in the preceding 5 years requiring intubation or mechanical ventilation, if they had a serious medical condition other than asthma, or if their caretaker planned to move from NOLA during the year.
BBB breakdown results in exacerbation of vasogenic cerebral edema which is one of the most life threatening complications post stroke [ 24, 25].
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