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Acting much like a molecular "mouse trap," cleavage of the sulfur-sulfur bond is thought to trigger a chain of events culminating in formation of a phenylene diradical, which removes hydrogen atoms from deoxyribonucleic acid (DNA).
In neurodegenerative disorders caused by polyglutamine (polyQ) expansion, polyQ toxicity is thought to trigger a linear cascade of successive degenerative events leading to neuronal death.
Liverpool have rejected an Arsenal club-record bid of £40m plus £1, a sum which is thought to trigger a clause in his contract allowing Suarez to be told of the offer and talk to Arsenal.
Stress, neglect and abuse, for example, is thought to trigger a cascade of signals that cause chemical markers to attach to a gene.
NIK-mediated nuclear relocalization of rpL10 is thought to trigger a defense response that impairs virus proliferation or spread.
Together with maternal malaria induced anemia [5], [6], parasite sequestration in the placenta are thought to trigger a pathological process that contributes to decrease fetal viability and leads to infant Low Birth Weight (LBW) [7], [8], due to both preterm delivery and/or Intrauterine Growth Retardation (IUGR) [9], [10].
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There is no cure for this overgrowth of cells, but patients can manage their symptoms by using antihistamines and avoiding medications that are thought to trigger an attack.
It's not the microbes, per se, that bring about the healing; rather, the infection is thought to trigger an immune response that is inhospitable to the tumour.
The etiopathology of BD remains uncertain, but infectious or environmental factors are thought to trigger an excessive immune and/or inflammatory response in genetically predisposed individuals.
In contrast, CCI is thought to trigger an immune response leading to a "neuritis" (Campbell and Meyer, 2006), where surgical lumbar sympathectomy produces no signification change in mechanical or cold allodynia (Kim et al., 1997).
Several types of inflammatory cells, including T cells or B cells, are regarded as particularly important in multiple sclerosis pathogenesis and thought to trigger demyelination and neurodegeneration in a non-specific 'bystander' fashion (Wisniewski and Bloom, 1975).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com