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"I thought, 'Substantial and quirky?
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For me, this is the first time in my life I've encountered a candidate who makes me think substantial change is possible".
I do not think substantial change will come from there.
Dudley, desperately seeking to avert damage from what he called "my case", was relieved to hear the impending outcome, but thought "another substantial company of honest men" should undertake a further investigation "for more knowledge of truth".
Therefore, it is thought that substantial amounts of these frameshifted aberrant proteins are produced in cells.
The president's going to need, I think, a substantial Democratic majority — that's where his support should begin.
And with so many negative spots, plus hit pieces flooding mailboxes, David Rohde, a political scientist at Michigan State University, said, "I think a substantial number of people have been put off by it".
But I don't think the substantial discrepancies in how the various Republican candidates poll against Mr. Obama should be neglected: there is clearly the chance that Republicans nominate someone who is too conservative to maximize their opportunity with swing voters.
"I think a substantial number of people who have criticized the decisions I have made have done so on a political basis for partisan motives and have used fear in a way to support their arguments," he said.
It's generating I think a substantial amount of revenue.
He thinks "a substantial step-up in infrastructure investment would serve all of our major economic objectives.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com