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The phrase "though up to now" is grammatically correct and can be used in written English, typically in more formal or academic writing.
It is often used to indicate a contrast or change of information from what was previously stated or assumed. Example: Though up to now, scientists believed the theory to be true, recent evidence has cast doubt on its validity.
Exact(2)
Indeed, even though up to now little work has been done by designers in penal institutions, it is a safe prediction that in a short time there will be considerable concern for the environmental qualities of these institutions, as well.
The high conservation of MIR168b suggests that it could be expressed and functional, even though, up to now, no experimental evidence has been reported.
Similar(58)
Though largely debated, up to now the use of neuroscience in legal contexts had not specifically been regulated by any legislation.
I have to admit, though, that up to now I have not been a great fan of the Obama administration.
Up to now, though, all I've heard from them is either "I'm weak, how can I compromise?" or "I'm strong, why should I compromise?" No happy medium, no stable Iraq.
Up to now, though, family caregivers have been largely ignored by policy makers, which is a mistake we must remedy, because "when we support family caregivers, we enable older adults to 'age in place' instead of in a high-cost institution," said Bedney.
I'm really mad about my little daughter and feel as though I had been up to now lacking some prime faculty: eyesight, hearing, reason.
The rest of it deals with the "for all time" part of the title, though he really means "up to now": the growth of the Shakespeare legend, the poet's reputation in the ages of Garrick and Romanticism, his ever-thriving career over the last two centuries and more, not only in Britain but pretty well everywhere.
Up to now, though, internal security and domestic Communism have been distinctly minor themes in the campaign, and this, too, has been a surprise to Goldwaterologists, who were certain that in due time a generous amount of McCarthyism would be stirred into the Goldwater brew.
Even though this concept appears attractive, up to now no studies have been presented investigating a possible correlation between elevated cellular cathepsin levels and sensitivity to apoptotic stimuli.
Besides, there are no data on the long term effects of mindfulness interventions in patients with OCD up to now, though mindfulness might be a valuable adjunct to CBT [ 32].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com