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Though more challenging to produce, antibacterial compounds that have novel structures, mechanisms of action and/or exploit previously unrecognized targets, as compared to those that have already reached the market, are the most logical choices for combating drug resistant pathogens (Donadio et al. 2010; Gwynn et al. 2010).
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Helping students to puzzle through different narrative perspectives or subtext or character motivation, though, can be much more challenging.
How it works at a proximate level, though, is a little more challenging for students to grasp.
On the road, though, life was more challenging.
The reformists' inability to communicate with the masses, though, is even more challenging.
Gov. Martin O'Malley of Maryland is scheduled to be on hand to sing the national anthems of the United States and Ireland in English and Gaelic respectively, though it might be more challenging the other way around.
For even longer cooking times, you can use a pot of water on the stove, though it will be more challenging to control the temperature.
We generated hydroxy-coated Pdots to remove such a surface charge, even though subsequent conjugation of ligands is more challenging.
Braking proved more challenging.
The nights were more challenging.
That makes it more challenging.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com