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In our experience, even though high doses of botulinum toxin are used in chronic migraine, the treatment is safe.
It is noteworthy that the beneficial effects of levodopa prevailed over its negative effects even though high doses of levodopa, associated with a peripheral decarboxylase inhibitor, were given.
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Though high dose of dichlorvos had a detrimental effect on acetylcholinesterase activity, no significant inhibition was seen with low dose of dichlorvos.
In addition, the probiotic C. butyricum was more effective than B. infantis, even though high dose of B. infantis was used.
In the term of serum biochemical analysis as shown in Fig. 3a, Diclo (7.4 and 14.8 mg/kg), Ibu (60 mg/kg), and Para (36.7 and 73.4 mg/kg) treatments had significantly changed values of ALT, though higher dose of Ibu (120 mg/kg) significantly reduced the elevation of ALT activity compared to the saline-treated group.
It should be noted, though, that high doses of GA of 0.2 1 µg/ml have been used in these reports.
There was widespread use in Israel earlier in the decade but little evidence of immediate or enduring harm, though high doses are potentially dangerous especially if used with other drugs and alcohol.
Animals displayed no tolerance development to LORR throughout the chronic exposure period even though moderate and high doses of ethanol were used.
Even though she was on high doses of diuretics, they were twice their usual size.
Oral immunosuppression was used in all 9 allograft patients because immune rejection has been reported to occur in 23.8% of cases in a series of allogeneic CLET who were nonimmunosuppressed even though the patients were given high doses of systemic steroids [ 26].
It's a relatively common procedure for injecting high doses of antibiotics, though it comes with frightening risks of infection.
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CEO of Professional Science Editing for Scientists @ prosciediting.com