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Thus, we believe that, upon TCR engagement and transcriptional activation, required "second signals" include those that prolong half-lives of many critical activation transcripts, and that this can be achieved through transmembrane signaling by a variety of molecules, including integrins.
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In addition, it is recommended that further work be undertaken in this context to produce standard and agreed sets of medications acknowledged to cause particular nontherapeutic effects that are known to be of concern in clinical trials, most particularly those medicinal products that prolong the QT interval and those that cause CYP modulation.
A physician with such a heart may better distinguish between treatments that prolong dying versus those that restore health.
Does there come a time when people no longer want to be subjected to shocks, even those that may prolong their lives?
It has been difficult to show significant survival benefits of many treatments (Malhi and Gores, 2006; Hong et al, 2007), although a recent survival difference in two chemotherapy regimes has been reported (Valle et al, 2010) and those that do prolong life may actually reduce quality of life.
Nuclear weapons can provide the beleaguered theocracy with immunities and concessions that prolong its life.
Physiological responses to pain create harmful effects that prolong the body's recovery after surgery.
If we supplied food to them would that prolong their extinction?
They should be used cautiously with drugs that prolong the QTc interval.
What are the key patient and healthcare professional factors that prolong diagnosis?
Dronedarone should not be used in conjunction with other drugs that prolong the QT interval.
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