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Still, those enzymes with particularly low vmax, as identified in this work, may very well be excellent candidates for those that exert the greatest degree of control over flux, but then the situation becomes continuous and non-linear, and cannot be captured by simply identifying a single enzyme with the lowest (in vitro) vmax.
These in vivo values are still orders of magnitude lower than those that exert effects in the present in vitro study.
But it may challenge the view that the factors that influence people's attendance during the scheme are likely to be similar to those that exert an influence after the scheme.
Chemomodulators belong to two categories, those that are transport substrates themselves and thereby compete for efflux and those that exert their effects by binding to and blocking drug efflux without themselves being transported out of the cell [ 24].
Comparing the locations of these SbiQTL with previously-detected imprinted QTL, i.e. those that exert a significant main effect on a given trait [ 10, 36], many QTL found here are novel loci with the exception of Sbi7.1 and those located on the proximal region on chromosome 3, which are within the confidence regions of previously described loci.
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Multi-variate sensitivity analysis was implemented to identify those parameters that exert a prominent role in the outputs of the model.
Exogenous variables represent those constructs that exert an influence on other constructs under study and are not influenced by other factors in the quantitative model.
In the model eukaryote, Saccharomyces cerevisiae, previous experiments have identified those genes that exert the most significant control over cell growth rate.
Another possibility is that FTO is just a proxy of as yet unidentified causal variants, and it is those variants that exert their effects on rs9939609 and influence pancreatic cancer risk.
By screening various antileishmanial compounds against L. donovani strains overproducing ODC, AdoMetDC or SpdS, it was possible to identify those compounds that exert their effect predominantly by interfering with the polyamine biosynthetic enzymes [ 95].
Further, the FCM helps to identify those factors that exert the greatest impact in a complex system, in this case: affordable/appropriate housing, access to social support services for those with addictions/mental illness, family support for those with children, positive community support and rental supplements.
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