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He was writing just as those favourable seasons were beginning for humans worldwide.
That pits those favourable towards public-service pluralism against the top-down tradition, those who want to soak the rich against the "intensely relaxed", the beer-n-bingo proletariat against the Islington pinot-ariat.
Harrison et al set out with the clear aim of focusing on members of the population categorised as passive positives (ie, those favourable to organ donation but not yet joined the register).
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Since this study was focused on the prognostic role of molecular tumour markers, an optimal cutoff point of marker index was determined that allowed best separation of patients into those with favourable and those with unfavourable clinical features and prognosis.
These patterns were similar in patients with unfavourable compared to those with favourable outcomes (Table 2).
There were no differences in the relative changes in blood lactate concentrations at any time point between patients with poor and those with favourable neurological outcomes (Table 1).
Cyclic and acyclic polyaminocarboxylate gadolinium complexes, especially those have favourable water exchange and tumbling rate for relaxation, have been reported to improve relaxivity and specificity.
On admission, median lactate concentrations (5.3[2.9 9.0] vs. 2.5[1.5 5.5], p < 0.001) and cardiovascular sequential organ failure assessment (cSOFA) score (3[0 4] vs. 0[0 3], p = 0.003) were higher in patients with poor than in those with favourable outcomes.
Lactate concentrations were higher on admission (5.3[2.9 9.0] vs. 2.5[1.5 5.5], p < 0.001) and at each time point thereafter in patients with poor than in those with favourable neurological outcome (Table 1 and Additional file 1: Figure S2).
Better survival was observed in younger patients, especially those with favourable NPI and screen-detected patients.
There is no significant effect on overall OS, although there was an OS benefit, based on cytogenetic analysis, in those with favourable core-binding factor translocations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com