Sentence examples for those endpoints require from inspiring English sources

Each of those endpoints require different military approaches for achieving them.

Since phase III definitive efficacy trials with cancer endpoints require a lengthy timeframe and considerable resources for completion, it is critical to first optimize agent delivery and trial design and to determine preliminary efficacy via the conduct of phase II trials.

Most of the respiratory diseases set as endpoints require a long time to develop to a level diagnosed clinically.

In the classical toxicological literature, it has always been assumed that transcriptome endpoints require phenotypic anchoring to other types of endpoints (Paules 2003; Waters and Fostel 2004).

Obviously, the different endpoints require the use of different regression techniques: linear regression (CRQ), Cox regression for recurrent events (exacerbations) and Cox or logistic regression for mortality.

However, trials that are dependent on clinical endpoints require relatively large numbers of patients due to heterogeneity of disease and placebo responses.

The challenge in finding anti-fibrotic therapies is partly due to the need of long and expensive clinical trials, as the currently used clinical endpoints require long study durations and a large number of patients [ 3].

We are aware that other assessments of potential surrogate endpoints require a two-step validation process, which involves: 1) establishing that the surrogate endpoint predicts the final endpoint accurately; 2) demonstrating that the effect of treatment on both the surrogate endpoint and the final endpoint is closely correlated [ 11].

In fact, many of the current environmental programs such as the European Water Framework Directive (WFD) or the US Clean Water Act do not explicitly test for EDCs, and considering the unique requirements and endpoints required to assess the endocrine potential of a sample, these programs are unlikely to appropriately address exposure to these chemicals.

Moreover, programs such as the European WFD or the US Clean Water Act do not explicitly test for EDCs, and considering the unique requirements and endpoints required to assess the endocrine potential of a sample, these programs are unlikely to appropriately address exposure to these chemicals.

For example, programs such as the European WFD (EC 2000/60/EG) or the US Clean Water Act do not explicitly test for EDCs, and considering the unique requirements and endpoints required to assess the endocrine potential of a sample, these programs are unlikely to appropriately address exposure to these chemicals.