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There's a message in those duplications perhaps.
Carlos Brito, the chief executive of the Belgian brewer InBev, refused to confirm that SAB's Mayfair headquarters would close, but said: "When two companies get together there will be duplications, particularly at the headquarters level, and we will have to deal with those duplications".
Because gene order can be shuffled due to inversions and translocations, those duplications are no longer expected to be in tandem.
Instead, the result suggests that the AO2 genes are heterogeneous in terms of their origins: if they all arose by HGT then the HGT events involved multiple donors, or if they all arose by gene duplication then those duplications occurred at multiple times.
Hypotheses relating to the function of the three aromatase paralogs depend in part on when those duplications took place.
For this purpose, we considered those duplications detected by the species overlap algorithm that only comprised paralogs as species-specific expansions.
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Those duplication events can be encoded in a binary duplication tree T with the items of V as the leaves.
Species-specific expansions were also detected by selecting those duplication nodes that only contained sequences from A. adeninivorans.
Both the copies of the original duplication of the CR CRII and CRII, Figure 1A to B) and CR- C-Y (CRI- C 1 -Y 1 and CR2- C'- Y', Figure 1E to F) can be explained by TDRL or other possible mechanisms, however, there is no clear indication to confirm which one is more suitable for those duplication events.
In contrast, recent gene duplications, those duplicated around the mammalian radiation or in the rodent lineage, are expected to have significant contributions to the gene robustness in the current mouse genome.
Previous results have demonstrated that after duplication those duplicates had a higher evolutionary rate, due to relaxation of purifying selection [ 2- 5].
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