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The dense dataset contains only those compounds of the sparse dataset where there are activity labels available for both BCRP and P-gp (161 compounds).
We identified those compounds of the most active fractions that displayed anti-proliferative activity.
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Biological oxidation of chlorophenol compounds is difficult because of toxic effects of those compounds on microorganisms.
Wound healing assays were employed to evaluate the effects of those compounds on the cell migratory ability.
We further tested the effects of those compounds by the addition of 500 µm of individual compounds together with or at intervals after the addition of DV to the cultured cells.
Some of those compounds in that sprig of thyme may well affect my digestion of the dish I add it to, helping to break down one compound or possibly stimulate production of an enzyme to detoxify another.
The abundance of those compounds increased after 15 days of storage.
The carcinogenic effects of several of those compounds have been detected through cancers that develop in industrial workers.
One important task is now to elucidate the mode of action of those compounds.
Studies on total synthesis and biotransformation of some of those compounds have been described.
Spectral determination of structure of those compounds was performed by NMR and ESI mass spectroscopy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com