These data also suggest that blocking cell cycle progression thorough downregulating cyclin D1 plays critical role in rexinoid-induced proliferation inhibition.
As some of these recurrences are associated with tumor progression, a thorough follow-up of these patients is of utmost importance.
Given their numerous putative roles in NPC development and progression, a thorough understanding of the impact of miRNA dysregulation in NPC is expected to shed light on useful biomarkers and therapeutic targets for the clinical management of this disease.
Up to date, little is known about the involvement of the individual HDAC isoforms in ALS onset and progression and a thorough survey of all isoforms has never been carried out.
A more thorough understanding of the pathological progression of disease in C3HeB/FeJ mice could facilitate modulation of the immune response to produce the desired pathology, increasing the utility of this animal model.
The role of the chef is changing, mostly for the better, although many in the trade wonder where the next generation is to receive the kind of thorough training it needs if this progression is to continue.
All these considerations show that knowledge on the contribution of human MDSCs to the tumor immuno-suppressive network and tumor progression emphasizes the need for thorough MDSC monitoring in cancer patients, to correlate MDSC percentages with clinical outcomes.
Design and implementation of multiple safety features demand thorough understanding of the sequences involved in accident progression.
18 27 A thorough literature search was conducted to identify disease progression data for each NYHA class, between January 2004 and December 2009.
A thorough qualitative discussion concerning the damage initiation and subsequent progression path at the skin-stringer joint is supported by the development of a simple analytical model based on the Classical Laminate Theory denominated as 3-spot-joint 3-spot-joint 3-spot-joint
However, in order to mitigate such volcano-related disasters, we need a thorough understanding of the activity status and stages of progression of volcanic activity.
