Exact(1)
Their overexpression causes mitotic defects [ 51,52], but a thorough loss of function analysis of the two paralogues, that may have overlapping substrate specificities, remains to be completed and systematic substrate identification has just begun [ 53].
Similar(59)
It was about the only bright spot in a thorough loss.
Here, the authors describe the cloning of Megf8 as well as the careful and thorough characterization of its loss-of-function.
As requested, our revision includes new data and additional text for a more thorough phenotypic analysis of Dnhe2 overexpression and loss-of-function.
A Stormforce spokesman added: "We have worked fully with the MAIB on its thorough investigation into the loss of Cheeki Rafiki and her four crew Andy, James, Paul and Steve.
We identified loss-of-function mutants and performed thorough genetic analyses of HLS1 and its homologs to characterize the effect, if any, these genes have on the ethylene response.
Despite the potential bias or selection due to loss of participants, our thorough non-participation analyses have shown that the data are broadly representative of the target population and that non-consenting is unlikely to distort the findings.
This unexpected sequence of events prompted a thorough assessment of possible causes for the loss of transgene expression.
Further studies are needed to investigate whether such ultrafiltration strategies result in more thorough fluid loss, fewer episodes of hypotension or better outcome.
A thorough characterization of the brain activity associated with loss of consciousness during anesthesia is of critical importance to better monitor patients undergoing anesthesia.
No deaths or injuries have resulted from the loss of any UAV and a thorough investigation is carried out into any incident that results in a UAV not being recovered or irreparably damaged.
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