While efforts to capture such encounters in aggregate terms have become increasingly sophisticated and thorough, the limitations just mentioned are part and parcel of epidemiological methods and simply cannot be overcome.
Each has its unique advantages and limitations; thorough overviews and comparisons between several NGS platforms are provided in [ 12– 12].
As original data collection in the consortium was not standardized and comprehensive across all these studies, we accounted for this limitation through thorough data harmonization and restriction to postmenopausal women aged 50 years and older.
An understanding of this phenomenon is critical for making good land management decisions based on a thorough understanding of the limitations of remote sensing data.
Supporting microbial communities in space requires a thorough understanding of the limitations of microbial life, interacting environmental parameters as well as factors such as asteroid structure and nutrient availability.
Whether simply comparing the relative intensities of two fluorescent specimens, or using advanced techniques like Förster resonance energy transfer (FRET) or fluorescence recovery after photobleaching (FRAP), quantitation of fluorescence requires a thorough understanding of the limitations of and proper use of the different components of the imaging system.
The research and final report produced may be driven by processes designed to ensure a comprehensive view of the market and reinforce the integrity of the report, but even the most thorough report has its limitations.
In general, a more thorough discussion of the limitations of the techniques should be discussed.
A more thorough discussion on the limitations of APHENA is available in the Supplemental Material (online at http://www.ehponline.org/members/2008/11345/suppl.pdf).org/members/2008/11345/suppl.pdf
Though the use of high throughput methylation analyses have rapidly advanced the field, a thorough understanding of the limitations of each platform is critical.
This would include, at the very least, a thorough discussion of the limitations and how they might affect the findings and implications of the study.
