In cases where there is a definite medical need for a particular drug, but the clinical diagnosis of drug allergy remains uncertain despite thorough investigations, a procedure to induce temporary drug tolerance (also referred to as drug desensitization) or graded challenge testing (also known as provocation testing) may be considered.
Despite thorough investigation of drug formulation, study procedures, and clerical data, the best explanation for the early inclination of benefit is the play of chance [ 6].
The Swansea-based region say a "thorough investigation" will be held in line with disciplinary procedures.
The Carillion spokesman said: "In line with our policies and procedures, we have carried out a thorough investigation into the collective grievance received from GMB members and take all the matters raised very seriously.
"A thorough investigation was held by the prison who immediately altered their procedures, and further changes were implemented across the prison estate".
Sophisticated strategic and private equity buyers usually follow strict due diligence procedures that will entail an intensive and thorough investigation of the selling company by multiple buyer employee and advisory teams.
"All police forces should have appropriate procedures in place to handle stalking cases, including a robust risk assessment followed by a thorough investigation". "The biggest help for me throughout this has been the National Stalking Helpline.
After a thorough investigation, we found no indication that any employee purposefully tampered with or circumvented any of those policies, processes or procedures, including our trademark filtering process.
A spokesman for North Lanarkshire Council's Learning and Leisure Services, said: "We have robust procedures in place and, when a child or young person is registered as being missing, a thorough investigation is immediately carried out.
Nikias said that Yang would "conduct a thorough investigation into the details of Carmen Puliafito's conduct, the university's response, as well as our existing policies and procedures". "All of us must cooperate fully and swiftly" with the investigation, the letter said.
A thorough investigation of the potential effects and interactions between the factors is made possible by rationally planning the trials using systematic procedures, i.e. design of experiments.
