A total of 213 Alu subfamilies have been reported based on a thorough computation of sequence homology in the human genome [ 2].
Finally, to be able to rely on the CFD computations done, one needs thorough validation.
We use a simulation-based approach founded on Approximate Bayesian Computation, which allows for a thorough exploration of parameter space as well as the quantification of uncertainty around best estimates.
The reader is referred to Maarleveld et al. (2013) for the thorough review of concept and application of this computation tool.
This performance and thorough result reporting leads to a substantially longer computation time.
This paper presents a thorough analysis of the smearing effect for three general contribution computation methods: complete decomposition, partial decomposition and reconstruction-based contributions.
Other approaches (e.g., Approximate Bayesian Computation or ABC) would probably allow a more thorough investigation of the parameters' space.
In this article, we focus on the tuning model specific to adaptive computations, implement the RSpring tuner for autonomic JEE servers, and perform a thorough evaluation on RSpring using industry standard benchmarks.
In a future work, we look to extend our study here into just such a thorough analysis and carefully consider the performance of the adjoint and hybrid derivative computation methods.
Although small pilot studies to assess data collection, indicator computation, data sending and data analyses are commonly executed prior to national PI implementation [ 6], thorough evaluations of reliability and validity of the PIs after implementation, are scarce [ 8, 9].
A thorough presentation of the analytical model is presented, along with its validation by comparison with the results of fully 3D computations.
