We simulate a network of 1000 recurrently connected excitatory spiking neurons with global feedback inhibition.
Chromosomal regions 8p12, 8q24, 11q13, 17q12 and 20q13 are recurrently amplified in breast cancers.
By analyzing the CRC cohort in The Cancer Genome Atlas (TCGA), we found that the Elf3 gene (located in 1q32.1) is recurrently amplified in CRC, and gained copy number variation significantly associates with increased mRNA expression level.
Twenty-seven of the 1144 genes were recurrently regulated after 131I and 211At exposure and divided into six clusters.
In countries like Egypt, Brazil, Greece, Thailand, Ukraine and beyond in the past six years, we've recurrently been witnessing the decline of state-society relations in which citizens believe in their leaders, political systems or certain policies less and less - and they have been speaking out in violent and non-violent ways.
In particular, of the 30%% of community-dwelling seniors who fall, half fall recurrently and are at significant risk for hospitalization, institutionalization, and even death [ 14– 16].
In our recent study which reported the chromosomal alterations in HCC by genome-wide array-CGH analysis, we found that a 1q21.3 locus was recurrently amplified and that a Tropomyosin 3 (TPM3) gene located in this region was coherently overexpressed in primary HCC [ 6].
High-level amplifications were observed in 33 regions and recurrently involved 11q22 (harbouring PDFG in 3 tumors), 11q13 (in 11 tumors, encompassing MYEOV, CCND1, FGF4, FGF3, PPFIA, FAD, TMEM16A, CTTS and SHANK2) and 7p11 (including EGFR in 4 tumors).
But as Hobbes saw four centuries ago, human history is recurrently unstable and dangerous.
Mecklenburg became Lutheran during the Protestant Reformation, and in the 16th and early 17th centuries the region was recurrently divided into two duchies, Mecklenburg-Schwerin (the west) and Mecklenburg-Güstrow (the east).
Since my release eight years ago I have thought recurrently that while prison is a human hell, it offers exceptional opportunities for inner peace by creating, if forcibly, a haven from the distractions of ordinary life.
