Within this organisation, decentralized operating units result in variability in the way components of the chronic care model are implemented and in the relative emphasis on each component.
In regards to dynamic reconfiguration issues, this approach is able to change the component's parameters, system's topology (i.e., the graph structure), or the way components store their data.
We call reconfiguration the actions consisting in changing at run-time the component structure, by adding or removing components in the system or by changing the way components are bound together.
Comparative systems biology scale approaches reveal that changes in phenotype are often a result of small changes in the way components interact or that similar biological outcomes can be achieved by networks of different components [ 13].
Rather than discuss ageing using multicellular organisms as paradigms, I accept the recent experimental data that demonstrate that bacteria age and take a slightly different stance, considering the way components in the cell age, with single-cell bacteria as reference organisms to see whether and how this relates to the way genomes are organised.
The details of the way component models can be integrated into a schematic capture system vary from system to system.
In this way, complicated components consisting of more than three reactants can be represented by the composition of components instantiated from these two patterns.
In this way, the components can be added or removed dynamically and will be recognized by the system transparently.
In this way, all components of detection, delay, and response can be properly weighted according to their contribution to the PPS as a whole.
In the same way, components of the tetanus [ 43], botulinum [ 44], and anthrax [ 45] toxins are believed to permeabilize the endosomal membrane to gain access to the cytosol.
