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Additional File 2 includes information about the significance level of all annotated metabolite peaks a) at each time point, as this was identified by MiTimeS, and b) in average over the thirty hours of treatment, as this was identified from paired-SAM, for all five physiological state comparisons indicated in Figure 1.

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This dependency was identified from free vibrations of aluminium EVA aluminium sandwich beams.

This peptide was identified from the T78 motif of a kinetochore component called PBIP1 (Kang et al. 2006).

This cohort was identified from a prospectively maintained database and included both elective and emergency operations.

This agent was identified from the blood of a hospitalized febrile patient and from opossums and their fleas.

This information was identified from review articles, extensive searches on PubMed, and text-mining platforms such as iHOP [ 24].

However, there was no unique geographic or temporal characteristic of Ph561, because this virus was identified from the patient from Tacloban City in December 2008.

A candidate informative marker, D6mit102, predicted to discriminate cell lines used in this study, was identified from the Jackson Laboratories informatics website (http://www.informatics.jax.org).org

This mitochondrial enzyme was identified from three spots, upregulated after 4 hours (spot 34) and downregulated after 8 and 24 hours (spot 35, 36).

In this study, Bosea thiooxidans was identified from 'wasta' sample.

The clone for this 'big' alk-SMase was identified from a human liver tumour.

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