This hypothesis warrants validation – while non-neuronal tissues are clearly convenient alternatives to post-mortem brain, questions remain as to how informative gene expression studies based on these samples will be.
Therefore, we concluded that pretreatment of phytohemagglutinin-induced IL2 mRNA levels in whole blood serve as a promising biomarker for predicting BiPN, and this finding warrants validation in a larger study.
56 57 However, unfavourable properties of current bioresorbable scaffolds (that is, thick struts, lower radial force than drug eluting stents, and narrower margins for overexpansion after deployment 58) could frustrate this approach, which warrants validation in targeted investigations in a sufficient number of patients.
This warrants experimental validation in rodent models of DS.
Patients with TN or HER2+ breast cancer probably need to be treated with a short STI or primary systemic therapy after CNB, but this warrants further validation.
Thus, a larger sample size may not detect this difference and this warrants further validation.> Loss of E Cadherin has been shown to be a strong predictor of surgical outcomes in a number of studies [ 18, 19].
This three-gene expression signature of poor-prognosis IBC warrants validation in larger series.
However, the demonstration that this family of genes is implicated in the regulation of aging in other organisms warrants validation in other species, particularly humans, and provides a novel regulatory axis for future studies on regulatory pathways that influence the aging process.
NSC 734406 correlated with low levels of Mre11 and Rad50 and therefore warrants validation and further study.
We propose the rs1152003 C/C genotype as a candidate genetic biomarker for ONJ, which warrants validation in larger series.
