This missense variation generates an amino acid exchange from asparagine to aspartate which reduces opioid receptor signaling efficiency and expression.
Additionally, most organisms have little physiological control over their own body temperatures, so that much of this ambient thermal variation generates corresponding variation in body temperatures.
Sequence variation generates different binding affinities, which correlate to protein import and export rates and therefore nuclear concentration.
Genetic variation generates phenotypic variation across the cells of an organ system, which are then subject to clonal selection through Darwinian competition.
The hypothesis that network structure, network plasticity and environment frequency predict population variation generates testable genomic predictions where these factors are known.
Epistatic interactions such as these can therefore be accommodated within this general framework of fitness variation generated by phenotypes other than antigenicity in driving patterns of influenza's antigenic evolution.
To this end I exploit variation generated by volatility in the U.S. economy between 1976 and 1996.
This could be attributed to variation generated by the length and the spatial orientation of the antibodies (both primary and secondary) that bound heterogeneously to the coatomer.
They argue that developmental processes determine variation by influencing the amount of variation generated as well as biasing the direction of variation generated.
Topography generates local-scale variation in soil properties that recapitulate landscape-scale variation generated by climate and parent material.
