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We selected a specific neoepitope as a candidate novel biomarker of lung disease, and developed an ELISA (ELM) for quantifying this unique target.
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Therefore, the specific advantage of this unique targeting mechanism utilized by XBP1u mRNA in vertebrates is unclear.
Molecular studies discussed in this article provide insights into the unique target cell specificity afforded by these analogues.
This result showed that IbTx could completely abolish the cell proliferation induced by martentoxin, which strongly implied that gBK channel was the unique target of martentoxin.
In contrast, the relative uniform overexpression of MELK in basal-like breast cancer makes this gene a unique target if its functional importance can be established.
The susceptibility of the rodent mammary gland to develop neoplasms has made this organ a unique target for testing the carcinogenic potential of specific genotoxic chemicals and environmental agents.
As one of the objectives of this study was to select a unique probe for a unique target sequence, we define "uniqueness" as (1) one non-redundant EST (unique target sequence) should be probed by one single non-redundant probe (unique probe) and (2) one unique probe should hybridize to one single unique target sequence.
In particular, this study unveiled several potentially unique target genes for each TF, such as RPN2 and HMGB1 being targeted by NFKB1.
Macrocyclic peptides designed to target this intermediate were synthesized with the goal of identifying compounds with specificity for this unique molecular target.
This acquired metabolism may provide a unique target for brain metastases using therapies that inhibit GABA metabolism.
This would help researchers choose a more unique target candidate and avoid SNP/insertion/deletion.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com