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This trial reported that administration of CAPIRI led to significantly lower PFS (5.8 months) in comparison with FOLFIRI, whereas the mOS was comparable between the two arms.
This trial reported that women experiencing local recurrence had a relative risk (RR) for developing distant disease 3.41-fold that of women free of local recurrence.
This trial reported that five patients were in a critical condition and eventually died during hospitalization, two from treatment group and three from control group.
A secondary analysis of this trial reported that, after correction of other risk factors, both early mobilization and increasing insulin dose independently prevented ICUAW [ 46].
This trial reported that 53% of patients experienced grade 3 or 4 adverse effects related to the therapy and 53% of patients had an objective response.
This trial reported that the risk of HRT treatment in the long-term use outweighed the benefits, due to the increased risk of breast cancer, stroke, thromboembolism, gallbladder disease and dementia [ 2].
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28 This might explain why some participants in the trial reported that physical activity helped to improve their mood.
Data from these interviews show that participants in the trial reported that they had read the booklets and this concurs with the significant increases in their knowledge scores.
The investigators in that trial reported that a positive fluid balance and elevated CVP were associated with increased mortality in patients with septic shock [ 25].
Even worse, a 2005 meta-analysis of 19 clinical trials reported that high doses of vitamin E (400 IU a day or more) were linked to an increased mortality rate.
Several trials reported that weight loss occurred in patients not experiencing nausea[ 21, 32, 35, 36, 41, 42].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com