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A similar approach was used in a subsequent clinical trial reported in 2011; this trial involved 14 patients suffering from heart failure who were scheduled to undergo cardiac bypass surgery.
This trial involved 2 interventions: within-prison initiation of methadone maintenance therapy and an evidence-based behavioral intervention adapted to the Malaysian context (the Holistic Health Recovery Program for Malaysia, HHRP-M).
This trial involved 159 patients.
This trial involved delayed randomisation.
This trial involved no primary interventions.
This trial involved a two-factor between-subject design (with/without baseline × relative/absolute risk reduction).
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This trial, involving 1,189 women followed for a year, was too small and short to determine that.
In addition, this trial involves little risk for manufacturers because patent extension does not depend on the outcome of the trial.
As this trial involves switching formulations of the same compound, we expect to find only small differences in efficacy but significant differences in tolerability and quality-of-life measures.
This trial involves 40 general practices and has recruited more than 500 patients.
This trial involves 2 active interventions PST and 'referral to the GP' and a 'waiting list control'.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com