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Why this trial has received so much attention is something of a mystery.
This trial has received NHS approval and results are expected in 2013.
This trial has received prospective ethics approval through the Latrobe University Human Research Ethics Committee.
This trial has received ethics approval from The University of Sydney Human Research Ethics Committee.
This trial has received human ethics approval from the Human Research Ethics Committee HRECC) of RMIT University (Project number 15/12).
This trial has received ethics approval from the Ethics Committee Heidelberg (approval No. S-261/2010), and is registered within clinical trails.gov (NCT01850875).
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Almost 45%% of patients in this trial had received prior systemic therapy, including methotrexate in about 17%% of patients.
3 Many of the children in this trial had received VAS at birth, and VAS had a negative effect on child survival.
The population recruited to this trial had received multiple courses of chemotherapy, and it would be interesting to evaluate the regimen in less chemo-resistant disease.
Caution however is needed when extrapolating these results to current patient populations since only 10%% of patients from this trial had received prior chemotherapy with or without adjuvant or neoadjuvant trastuzumab.
Since opening in late May, the trial has received almost no media attention.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com