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This trial comprises of part of the work undertaken by Theme 5. Ethical approval has been obtained from South Birmingham Ethics Committee (10/H1207/23) Approval at each site has been obtained from the local Research and Development Directorates.
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This trial comprises the selection of RIT candidate patients on the basis of pretherapy SPECT imaging and dosimetry.
The corifollitropin alfa regimen used in this trial comprised a single dose of corifollitropin alfa followed by daily doses of rFSH (as needed up to a daily maximum of 200 IU).
The trial comprised of 9 healthy volunteers under fasted conditions.
The exercise trial comprised of 10 × 10 s running sprints, interspersed by 50 s active recovery (walking).
Children were included in four trials but only one trial comprised of children only.
The trial comprised of five visits: Baseline (entry visit), week one, week 2, week 6 and week 12 (study end).
The trial comprised of an intervention arm of 53,890 women assigned to annual screening invitation and a control arm of 106,971 women not offered screening.
The double-blind phase III trial comprised of up to 6 weekly treatments over 8 weeks, 4 weekly evaluation visits, and then monthly follow-up; open-label dosing began as needed after three blinded treatments.
In this task, 120 trials comprised of a bilateral black and white checkerboards and binaural tone stimulation at one of three frequencies (300, 600, or 1,200 Hz, equal number of trials pseudorandomly ordered) with a duration of 34 and 300 ms, respectively.
One hundred and four trials comprising of 112 trial arms were included in this analysis (for references see Appendix A).
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