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This transcript is not efficiently, if at all, translated into Atg31 protein, as scanning ribosomes (Kozak 2005) attaching at the 5′ end of the extended transcript would encounter start and stop codons before reaching the ATG31 start codon.
Of note, this transcript is not documented in any human gene databases, although the existence of human expressed sequence tags (ESTs) at this locus further supports the validity of this TAR.
PNPase and RNase E appear to have a role in rbcL maturation that leads to degradation of the intergenic region, as this transcript is not detectable in the WT.
Similar(57)
This transcript was not significantly upregulated.
This transcript was not detected in any of the somatic tissues (Additional file 9).
However, this transcript was not significant after controlling for multiple testing.
(F ) as in (C ), except this transcript was not predicted to undergo readthrough.
However, this transcript was not detected in 555 gastrointestinal and 90 breast cancers.
(G ) as in (D ), except this transcript was not predicted to undergo single or double readthrough.
This transcript was not present in oocytes and was found only in the ovarioles (Additional file 2).
Interestingly, expression of this transcript was not detected in the post-neap sample (i.e., following gamete release), suggesting that it may be localized to mature oogonia.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com